Posterior segment optical coherence tomography findings in patients with COVID-19

Year 2023, Volume: 5 Issue: 1, 1 - 6, 20.02.2023

Alev Koçkar Hayati Yılmaz Betül İlkay Sezgin Erdal Yüzbaşıoğlu

https://doi.org/10.52827/hititmedj.1124153

Abstract

Abstract:
Purpose: COVID – 19 which is still the leading health problem in the world, is not yet fully understood, therefore the study aims to investigate the posterior segment of the eye in patients with COVID – 19 using optical coherence tomography (OCT).
Materials and Methods: The present study was designed prospective and cross-sectional. Patients with a positive test result of COVID – 19 and healthy controls who were older than 18 years were included in the study. Excluded from the study were the patients with any systemic comorbidity and ocular disease. The demographic and clinical data, including ocular findings and the OCT data, including hyper-reflective (HR) lesions, retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and macular thicknesses (MT) were recorded as outcomes and analyzed.
Results: Twenty patients with SARS-CoV-2 and 20 healthy subjects were included in this study. There was no difference between COVID -19 patients and healthy controls in terms of the RNFL, GCC, and macular thicknesses (P > 0.05). HR lesions were detected in 18(45%) eyes of 9(45%) patients with COVID – 19 and 15(37,5%) eyes of 8(40%) healthy subjects’ retinae with no significant difference between groups (P = 0.165).
Conclusions: Hyper-reflective lesions could only be retinal vessels' tangential cuts seen in OCT B-Scans. There was not enough data that could indicate posterior segment involvement of COVID – 19.

Keywords

COVID-19, retina, optical coherence tomography, macular thickness, retina nerve fiber layer thickness

Supporting Institution

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Project Number

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Thanks

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COVID -19 hastalarında arka segment optik koherens tomografi bulguları

Abstract

Amaç:
Kliniği tam olarak anlaşılamamış olan COVID – 19, hala dünyanın önde gelen sağlık problemi olmaya devam etmektedir. Bu nedenle bu çalışmada optik koherens tomografi (OKT) kullanılarak COVID – 19 hastalarının gözlerinin arka segmentini araştırmayı amaçladık.
Gereç ve Yöntem:
Çalışma prospektif ve kesitsel olarak tasarlanmıştır. Onsekiz yaşından büyük COVID – 19 test sonucu pozitif olan hastalar ve sağlıklı kontroller çalışmaya dahil edilmiştir. Göz ya da sistemik komorbiditesi olan hastalar çalışma dışı bırakılmıştır.Göz muayene bulguları, hiper-reflektiv lezyonlar (HR lezyon), retina sinir lifi tabakası (RSLT), ganglion hücre kompleksi (GHK) ve maküler kalınlıkları (MK) olmak üzere OKT verilerini de içeren demografik ve klinik veriler kayıt edilmiş ve sonuçlar analiz edilmiştir.
Bulgular:
Yirmi COVID – 19 hastası ve 20 sağlıklı göznüllü çalışmaya dahil edilmiştir. Sağlıklı gönüllüler ile hastalar arasında RSLT, GHK ve MK açısından anlamlı fark görülmemiştir (P > 0.05). HR lezyonlar 9 (%45) hastanın 18 (%45) gözünde ve 8 (%40) sağlıklı gönüllünün 15 (%37,5) gözünün retinalarında tespit edildi. HR lezyon varlığı açısından gruplar arasında anlamlı bir fark tespit edilmemiştir.
Sonuç:
Hiper-reflektiv lezyonlar yalnızca retinal damarların OKT B taramalarında izlenen tanjansiyal kesiti olabilir. COVID – 19’un gözün arka segmentini etkileyebiliceğini gösteren yeterli veri elde edilememiştir.

Keywords

COVID-19, retina, optik koherens tomografi, maküler kalınlık, retina sinir lifi tabakası

Project Number

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