Case Report
Year 2016,
Volume: 1 Issue: 1, 1 - 6, 15.08.2016
Abstract
Son
yıllarda yapılan epidemiyolojik çalışmalarda D vitamini eksikliği ile diabetes
mellitus gelişimi arasında ilişki gösterilmiştir. Deneysel çalışmalar da D
vitaminin diabetes mellitus patogenezinde rolü olabileceği görüşünü desteklemektedir.
Ayrıca D vitamini replasmanının uzun dönemde diabetes mellitus gelişme riskini
azaltabileceği bildirilmektedir. Vitamin
D’nin insülin direnci ve beta hücre disfonksiyonu üzerine reseptörü üzerinden
direkt ve kalsiyum homeostazını etkileyerek indirekt etkileri olabileceği
belirtilmektedir. Bu olgu
sunumumuzda, bazal-bolus insülin tedavisi alan ve kan şekeri regülasyonu
sağlanmakta zorlanan 49 yaşında tip 2 diyabetes mellituslu bir kadın hastanın D
vitamini replasmanı ile insülin ihtiyacının azaldığını ve kan şekeri
regülasyonun daha kolay sağlandığını bildirdik.
Keywords
References
- 1. Abou-Seif MA, Youssef A-A. Evaluation of some biochemical changes in diabetic patients. Clinica Chimica Acta 2004, 346(2):161-170.
- 2. Pittas AG, Sun Q, Manson JE, et al. Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in women. Diabetes Care 2010, 33(9):2021-2023.
- 3. Mathieu C, Gysemans C, Giulietti A, et al. Vitamin D and diabetes. Diabetologia 2005, 48(7):1247-1257.
- 4. Lips P. Vitamin D physiology. Prog Biophys Mol Biol 2006, 92(1):4-8.
- 5. Chiu KC, Chu A, Go VLW, et al. Hypovitaminosis D is associated with insulin resistance and β cell dysfunction. The American journal of clinical nutrition 2004, 79(5):820-825.
- 6. Teegarden D, Donkin SS. Vitamin D: emerging new roles in insulin sensitivity. Nutrition research reviews 2009, 22(01):82-92.
- 7. Billaudel BJ, Delbancut AP, Sutter BC, et al. Faure AG: Stimulatory effect of 1, 25-dihydroxyvitamin D 3 on calcium handling and insulin secretion by islets from vitamin D 3-deficient rats. Steroids 1993, 58(7):335-341.
- 8. Pittas AG, Lau J, Hu FB, et al. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. The Journal of Clinical Endocrinology & Metabolism 2007, 92(6):2017-2029.
- 9. Gagnon C, Lu ZX, Magliano DJ, et al. Serum 25-hydroxyvitamin D, calcium Intake, and risk of type 2 diabetes after 5 years results from a national, population-based prospective study (the Australian Diabetes, Obesity and Lifestyle Study). Diabetes Care 2011, 34(5):1133-1138.
- 10. Inzucchi SE, Maggs DG, Spollett GR, et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. New England Journal of Medicine 1998, 338(13):867-873.
Year 2016,
Volume: 1 Issue: 1, 1 - 6, 15.08.2016
Abstract
References
- 1. Abou-Seif MA, Youssef A-A. Evaluation of some biochemical changes in diabetic patients. Clinica Chimica Acta 2004, 346(2):161-170.
- 2. Pittas AG, Sun Q, Manson JE, et al. Plasma 25-hydroxyvitamin D concentration and risk of incident type 2 diabetes in women. Diabetes Care 2010, 33(9):2021-2023.
- 3. Mathieu C, Gysemans C, Giulietti A, et al. Vitamin D and diabetes. Diabetologia 2005, 48(7):1247-1257.
- 4. Lips P. Vitamin D physiology. Prog Biophys Mol Biol 2006, 92(1):4-8.
- 5. Chiu KC, Chu A, Go VLW, et al. Hypovitaminosis D is associated with insulin resistance and β cell dysfunction. The American journal of clinical nutrition 2004, 79(5):820-825.
- 6. Teegarden D, Donkin SS. Vitamin D: emerging new roles in insulin sensitivity. Nutrition research reviews 2009, 22(01):82-92.
- 7. Billaudel BJ, Delbancut AP, Sutter BC, et al. Faure AG: Stimulatory effect of 1, 25-dihydroxyvitamin D 3 on calcium handling and insulin secretion by islets from vitamin D 3-deficient rats. Steroids 1993, 58(7):335-341.
- 8. Pittas AG, Lau J, Hu FB, et al. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. The Journal of Clinical Endocrinology & Metabolism 2007, 92(6):2017-2029.
- 9. Gagnon C, Lu ZX, Magliano DJ, et al. Serum 25-hydroxyvitamin D, calcium Intake, and risk of type 2 diabetes after 5 years results from a national, population-based prospective study (the Australian Diabetes, Obesity and Lifestyle Study). Diabetes Care 2011, 34(5):1133-1138.
- 10. Inzucchi SE, Maggs DG, Spollett GR, et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. New England Journal of Medicine 1998, 338(13):867-873.
There are 10 citations in total.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Makale |
| Authors | |
| Publication Date | August 15, 2016 |
| Published in Issue | Year 2016 Volume: 1 Issue: 1 |