An Effective Method to Synthesize 2,3-Dihydroquinazolin-4(1H)- One Using Phosphate Fertilizers (MAP, DAP and TSP) as Green Heterogeneous Catalysts

Year 2018, , 303 - 316, 01.09.2017

Youssef Merroun Soukaina Chehab Touriya Ghaılane Said Boukhrıs Rachida Ghaılane Nouzha Habbadı Amina Hassıkou Brahim Lakhrıssı Abdelaziz Souızı

https://doi.org/10.18596/jotcsa.363818

Cited By: 3

Abstract

In this work, an efficient, easy, and
green process has been developed for the synthesis of
2,3-dihydroquinazolin-4(1H)-one from a condensation reaction of anthranylamide
with various aromatic aldehyde using of phosphate fertilizers, mono-ammonium
phosphate (MAP), di-ammonium phosphate (DAP) and triple super phosphate (TSP) as heterogeneous catalysts. The reaction conditions were
optimized taking into account of some parameters which control the reaction,
namely the nature and the volume of the solvent and the mass of catalyst. The results show that the catalysts used herein are very
interesting because they present a good catalytic activity and they are
reusable for at least five cycles without any degradation of their activity.

Keywords

Heterogeneous catalysis, fertilizer phosphate, MAP, DAP

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