Rize Yöresine ait Farklı Meyve Çeşitlerinin Antimikrobiyal ve Quorum Sensing İnhibisyon Potansiyellerinin Belirlenmesi

Year 2024, Volume: 24 Issue: 1, 74 - 80, 03.04.2024

Ülkü Zeynep Üreyen Esertaş İnci Durukan Ali Osman Kılıç Saliha Ekşi

https://doi.org/10.17475/kastorman.1460605

Abstract

Çalışmanın Amacı: Son yıllarda hızla artan antibiyotik direnç, halk sağlığı için ciddi bir tehdit oluşturmaktadır. Yapılan çalışmalar, bu direnç sorununun korkutucu sayılarla ifade edilen şekilde özellikle 2050'li yıllarda büyük oranlarda can kaybına neden olacağını belirtmektedir. Bu nedenle, çalışma kapsamında Rize iline ait çeşitli meyveler antimikrobiyal ve anti-quorum sensing aktiviteleri açısından taranmıştır.
Çalışma alanı: Bu araştırma, Rize, Türkiye'nin Karadeniz Bölgesi'nin kuzey kısmında yer alan İkizdere'de gerçekleştirildi.
Materyal ve yöntem: Örneklerin antimikrobiyal aktiviteleri agar kuyucuk yöntemi ile ölçülürken, quorum sensing aktivite agar kuyucuk ve spektrofotometre ile ölçüldü.
Temel sonuçlar: Çalışma sonuçları özellikle Cornus mas bitkisinin potansiyel antimikrobiyal ve quorum sensing özellik taşıdığını göstermektedir.
Araştırma vurguları: Özellikle Cornus mas bitkisinin farklı özütlerinin ve kimyasal özelliklerinin araştırılmasının önemli olacağı düşünülmektedir.

Keywords

Quorum Sensing, Piyosiyanin, Cornus mas

Determination of Antimicrobial and Quorum Sensing Inhibition Potentials of Different Types of Berries from Rize

Abstract

Aim of the study: The rapid increase in antibiotic resistance in recent years poses a major threat to public health. Studies indicate that this resistance issue, expressed in alarming numbers, will lead to significant loss of life, particularly in the 2050s. Therefore, various fruits from the Rize province were screened in this study for their antimicrobial and anti-quorum sensing activities.
Area of study: The investigation took place in İkizdere, situated within the northern part of the Black Sea region in Rize, Türkiye.
Material and methods: While antimicrobial activities of the samples were measured by agar well diffusion method, quorum sensing activity was measured with an agar well and spectrophotometer.
Main results: The results of the study show that the Cornus mas plant has potential antimicrobial and quorum sensing properties.
Research highlights: It is thought that it will be important to investigate the different extracts and chemical properties of the Cornus mas plant.

Keywords

Quorum Sensing, Pyocyanin, Cornus mas

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