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Özofagus ve Mide Kanserinin Retrospektif Analizi

Year 2022, , 188 - 194, 30.06.2022
https://doi.org/10.18663/tjcl.1039557

Abstract

Amaç: Özofagus ve mide kanseri en sık görülen ve ölümcül maligniteler arasındadır. Bu çalışmada yeni özofagus ve mide
kanseri tanısı alan hastaların verilerinin retrospektif olarak değerlendirilmesi amaçlandı.
Gereç ve Yöntem: Çalışmaya özofagus kanseri tanısı almış 271 hasta ve mide kanseri tanısı alıp total/subtotal gastrektomi
yapılmış 352 hasta dahil edildi.
Bulgular: Özofagus kanseri tanılı hastalarda yaş ortalaması 63 ± 13,2 iken mide kanserli hastalarda 64,6 ± 11,5 idi.
Özofagus kanseri tanılı hastalarda en sık görülen histopatolojik tip %77,5 ile skuamöz hücreli karsinom iken mide kanseri
tanılı hastalarda en sık görülen histopatolojik tip %92,6 ile adenokarsinom idi. Özofagus kanserli hastalarda en sık görülen
tümör yerleşimi özofagusun alt üçte biri iken mide kanserli hastalarda korpus idi. Mide kanserli hastaların %5,9'u erken
evre mide kanseri olarak kabul edildi. Hem özofagus hem de mide kanserli hastalarda cinsiyetin, tümör lokalizasyonunun
veya histopatolojik tipin sağkalım açısından anlamlı fark oluşturmadığı görüldü.
Sonuç: Ülkemizde sık görülen ve mortalitesi yüksek olan özofagus ve mide kanserlerinin erken tanısı için ulusal tarama
programları uygulanması düşünülebilir.

References

  • 1. Mayer RJ. Upper Gastrointestinal Tract Cancers. In: Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J (eds). Harrison’s Principles of Internal Medicine. 19th ed. New York: McGraw-Hill; 2015: 532-7.
  • 2. D’Journo XB, Thomas PA. Current management of esophageal cancer. J Thorac Dis 2014; 6: 253-64.
  • 3. Tuncer İ, Uygan İ, Kösem M, et al. The demography and histopathologic characteristics of upper gastrointestinal cancers appeared in Van and its vicinity. Van Med J 2001; 8: 10-3.
  • 4. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68: 394-424.
  • 5. Tuncer İ, Topçu N, Uğraş S, et al. The distribution of gastrointestinal cancers in region of lake Van. T Klin J Gastroenterohepatol 2003; 14: 161-6.
  • 6. Yalcin S. Gastric cancer in Turkey—a bridge between West and East. Gastrointest Cancer Res 2009; 3: 29-32.
  • 7. Bollschweiler E, Berlth F, Baltin C, et al. Treatment of early gastric cancer in the Western World. World J Gastroenterol 2014; 20: 5672-8.
  • 8. Faria GR, Pinto-de-Sousa J, Preto JR, et al. Three decades of clinical-pathological trends in gastric cancer: prospective data from a Portuguese hospital. Int J Surg 2013; 11: 472-6.
  • 9. Mathieu LN, Kanarek NF, Tsai HL, et al. Age and sex differences in the incidence of esophageal adenocarcinoma: results from the Surveillance, Epidemiology, and End Results (SEER) Registry (1973–2008). Dis Esophagus 2014; 27: 757-63.
  • 10. Coşkun A, Borazan S, Yükselen V, et al. Features of upper gastrointestinal tract malignancies in Aydın region. Endoscopy Gastrointestinal 2015; 23: 67-9.
  • 11. Albayrak F, Ozturk Y, Dursun H, Albayrak Y. Should every region use the same gastric cancer scanning and treatment approaches? Let’s reconsider: a northeastern Turkey example. BMC Gastroenterol 2016; 16: 120.
  • 12. Şahin M, Tanrıkulu Y, Erel S, et al. Our experience of gastrectomy for gastric cancer. Bidder Tıp Bilimleri Dergisi 2010; 2: 20-6.
  • 13. Sezer TÖ, Tosun S, Görgün M, et al. Surgical treatment of gastric cancer: retrospective analysis of 172 patients. Tepecik Eğit Hast Derg 2010; 20: 70-6.
  • 14. Siewert JR, Böttcher K, Stein HJ, Roder JD. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998; 228: 449-61.
  • 15. Maehara Y, Watanabe A, Kakeji Y, et al. Prognosis for surgically treated gastric cancer patients is poorer for women than men in all patients under age 50. Br J Cancer 1992; 65: 417-20.
  • 16. Liu S-Z, Wang B, Zhang F, et al. Incidence, survival and prevalence of esophageal and gastric cancer in Linzhou city from 2003 to 2009. Asian Pac J Cancer Prev 2013; 14: 6031-4.
  • 17. Kısaoğlu A, Özoğul B, Yıldırgan Mİ, et al. Surgery in the gastric cancer: 504 cases. Abant Med J 2014; 3: 220-5.
  • 18. Turner JR, Lingen MW. Oral Cavity and Gastrointestinal Tract. In: Kumar V, Abbas AK, Aster JC (eds). Robbins Basic Pathology. 9th ed. Philadelphia: Elsevier/Saunders; 2013: 551-602.
  • 19. Türkyılmaz A, Eroğlu A, Aydın Y, et al. Survival in esophageal cancer patients with hematogenous distant organ metastases. Turk J Med Sci 2009; 39: 415-21.
  • 20. Kama NA, Atlı M, Dağlar G, et al. Surgical treatment of gastric cancer: 11-year experience. Turkiye Klinikleri J Med Sci 2005; 25: 538-45.
  • 21. Noguchi Y, Morinaga S, Yamamoto Y, Yoshikawa T. Is there a role for nontraditional resection of early gastric cancer? Surg Oncol Clin N Am 2002; 11: 387-403.
  • 22. Selcukbiricik F, Tural D, Bilici A, et al. Clinicopathological features and localization of gastric cancers and their effects on survival in Turkey. Asian Pac J Cancer Prev 2013; 14: 553-6.
  • 23. Kaçan T, Babacan NA, Kılıçkap S, et al. Prognostic factors in patients with non-metastatic gastric cancer. Cumhuriyet Med J 2013; 35: 326-31.
  • 24. Koç HO, Sari YS, Bektaş H, et al. Do we adequately diagnose early gastric cancer in Turkey. Turk J Gastroenterol 2011; 22: 255-9.
  • 25. Türkyılmaz A, Aydın Y. Diagnostic techniques in esophageal diseases. Toraks Cerrahisi Bülteni 2011; 2: 242-53.
  • 26. Kotan Ç, Kisli E, Sönmez R, et al. Our experiences in surgical treatment of esophageal cancer: Analysis of 57 cases. Van Med J 2001; 8: 54-60.
  • 27. Erikoğlu M, Yol S, Tavlı Ş, et al. Gastric cancers: Our fifteen years experiences. Genel Tıp Derg 2005; 15: 71-5

A Retrospective Analysis of Esophagus and Gastric Cancer

Year 2022, , 188 - 194, 30.06.2022
https://doi.org/10.18663/tjcl.1039557

Abstract

Aim: Esophageal and gastric cancer are among the most commonly seen and fatal malignancies. In this study we aimed
to evaluate the data of patients who were newly diagnosed with esophagus and gastric cancer.
Material and Methods: 271 patients that were diagnosed with esophageal cancer and 352 patients that were diagnosed
with gastric cancer and had undergone total/subtotal gastrectomy were investigated in this study.
Results: The mean age was 63 ± 13.2 years for patients with esophageal cancer, and 64.6 ± 11.5 for patients with gastric
cancer. The most common histopathological type in patients with esophageal cancer was squamous cell carcinoma
(77.5%) and the most common histopathological type in patients with gastric cancer was adenocarcinoma (92.6%). The
most common tumor location in patients with esophageal cancer was lower third of esophagus and the most common
tumor location in patients with gastric cancer was corpus. 5.9% of patients with gastric cancer were accepted as early
stage gastric cancer. There were no significant differences between the groups in terms of survival according to gender,
tumor localization or histopathological types in patients with esophageal or gastric cancer.
Conclusion: National screening programs may be considered for early diagnosis of esophageal and gastric cancers, which
are common and have high mortality rates in Turkey

References

  • 1. Mayer RJ. Upper Gastrointestinal Tract Cancers. In: Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J (eds). Harrison’s Principles of Internal Medicine. 19th ed. New York: McGraw-Hill; 2015: 532-7.
  • 2. D’Journo XB, Thomas PA. Current management of esophageal cancer. J Thorac Dis 2014; 6: 253-64.
  • 3. Tuncer İ, Uygan İ, Kösem M, et al. The demography and histopathologic characteristics of upper gastrointestinal cancers appeared in Van and its vicinity. Van Med J 2001; 8: 10-3.
  • 4. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018; 68: 394-424.
  • 5. Tuncer İ, Topçu N, Uğraş S, et al. The distribution of gastrointestinal cancers in region of lake Van. T Klin J Gastroenterohepatol 2003; 14: 161-6.
  • 6. Yalcin S. Gastric cancer in Turkey—a bridge between West and East. Gastrointest Cancer Res 2009; 3: 29-32.
  • 7. Bollschweiler E, Berlth F, Baltin C, et al. Treatment of early gastric cancer in the Western World. World J Gastroenterol 2014; 20: 5672-8.
  • 8. Faria GR, Pinto-de-Sousa J, Preto JR, et al. Three decades of clinical-pathological trends in gastric cancer: prospective data from a Portuguese hospital. Int J Surg 2013; 11: 472-6.
  • 9. Mathieu LN, Kanarek NF, Tsai HL, et al. Age and sex differences in the incidence of esophageal adenocarcinoma: results from the Surveillance, Epidemiology, and End Results (SEER) Registry (1973–2008). Dis Esophagus 2014; 27: 757-63.
  • 10. Coşkun A, Borazan S, Yükselen V, et al. Features of upper gastrointestinal tract malignancies in Aydın region. Endoscopy Gastrointestinal 2015; 23: 67-9.
  • 11. Albayrak F, Ozturk Y, Dursun H, Albayrak Y. Should every region use the same gastric cancer scanning and treatment approaches? Let’s reconsider: a northeastern Turkey example. BMC Gastroenterol 2016; 16: 120.
  • 12. Şahin M, Tanrıkulu Y, Erel S, et al. Our experience of gastrectomy for gastric cancer. Bidder Tıp Bilimleri Dergisi 2010; 2: 20-6.
  • 13. Sezer TÖ, Tosun S, Görgün M, et al. Surgical treatment of gastric cancer: retrospective analysis of 172 patients. Tepecik Eğit Hast Derg 2010; 20: 70-6.
  • 14. Siewert JR, Böttcher K, Stein HJ, Roder JD. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998; 228: 449-61.
  • 15. Maehara Y, Watanabe A, Kakeji Y, et al. Prognosis for surgically treated gastric cancer patients is poorer for women than men in all patients under age 50. Br J Cancer 1992; 65: 417-20.
  • 16. Liu S-Z, Wang B, Zhang F, et al. Incidence, survival and prevalence of esophageal and gastric cancer in Linzhou city from 2003 to 2009. Asian Pac J Cancer Prev 2013; 14: 6031-4.
  • 17. Kısaoğlu A, Özoğul B, Yıldırgan Mİ, et al. Surgery in the gastric cancer: 504 cases. Abant Med J 2014; 3: 220-5.
  • 18. Turner JR, Lingen MW. Oral Cavity and Gastrointestinal Tract. In: Kumar V, Abbas AK, Aster JC (eds). Robbins Basic Pathology. 9th ed. Philadelphia: Elsevier/Saunders; 2013: 551-602.
  • 19. Türkyılmaz A, Eroğlu A, Aydın Y, et al. Survival in esophageal cancer patients with hematogenous distant organ metastases. Turk J Med Sci 2009; 39: 415-21.
  • 20. Kama NA, Atlı M, Dağlar G, et al. Surgical treatment of gastric cancer: 11-year experience. Turkiye Klinikleri J Med Sci 2005; 25: 538-45.
  • 21. Noguchi Y, Morinaga S, Yamamoto Y, Yoshikawa T. Is there a role for nontraditional resection of early gastric cancer? Surg Oncol Clin N Am 2002; 11: 387-403.
  • 22. Selcukbiricik F, Tural D, Bilici A, et al. Clinicopathological features and localization of gastric cancers and their effects on survival in Turkey. Asian Pac J Cancer Prev 2013; 14: 553-6.
  • 23. Kaçan T, Babacan NA, Kılıçkap S, et al. Prognostic factors in patients with non-metastatic gastric cancer. Cumhuriyet Med J 2013; 35: 326-31.
  • 24. Koç HO, Sari YS, Bektaş H, et al. Do we adequately diagnose early gastric cancer in Turkey. Turk J Gastroenterol 2011; 22: 255-9.
  • 25. Türkyılmaz A, Aydın Y. Diagnostic techniques in esophageal diseases. Toraks Cerrahisi Bülteni 2011; 2: 242-53.
  • 26. Kotan Ç, Kisli E, Sönmez R, et al. Our experiences in surgical treatment of esophageal cancer: Analysis of 57 cases. Van Med J 2001; 8: 54-60.
  • 27. Erikoğlu M, Yol S, Tavlı Ş, et al. Gastric cancers: Our fifteen years experiences. Genel Tıp Derg 2005; 15: 71-5
There are 27 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Orıgınal Artıcle
Authors

Canan Birdal This is me 0000-0002-8635-6782

Hakan Dursun This is me 0000-0003-3449-7118

Onur Can Kılınç

Publication Date June 30, 2022
Published in Issue Year 2022

Cite

APA Birdal, C., Dursun, H., & Kılınç, O. C. (2022). A Retrospective Analysis of Esophagus and Gastric Cancer. Turkish Journal of Clinics and Laboratory, 13(2), 188-194. https://doi.org/10.18663/tjcl.1039557
AMA Birdal C, Dursun H, Kılınç OC. A Retrospective Analysis of Esophagus and Gastric Cancer. TJCL. June 2022;13(2):188-194. doi:10.18663/tjcl.1039557
Chicago Birdal, Canan, Hakan Dursun, and Onur Can Kılınç. “A Retrospective Analysis of Esophagus and Gastric Cancer”. Turkish Journal of Clinics and Laboratory 13, no. 2 (June 2022): 188-94. https://doi.org/10.18663/tjcl.1039557.
EndNote Birdal C, Dursun H, Kılınç OC (June 1, 2022) A Retrospective Analysis of Esophagus and Gastric Cancer. Turkish Journal of Clinics and Laboratory 13 2 188–194.
IEEE C. Birdal, H. Dursun, and O. C. Kılınç, “A Retrospective Analysis of Esophagus and Gastric Cancer”, TJCL, vol. 13, no. 2, pp. 188–194, 2022, doi: 10.18663/tjcl.1039557.
ISNAD Birdal, Canan et al. “A Retrospective Analysis of Esophagus and Gastric Cancer”. Turkish Journal of Clinics and Laboratory 13/2 (June 2022), 188-194. https://doi.org/10.18663/tjcl.1039557.
JAMA Birdal C, Dursun H, Kılınç OC. A Retrospective Analysis of Esophagus and Gastric Cancer. TJCL. 2022;13:188–194.
MLA Birdal, Canan et al. “A Retrospective Analysis of Esophagus and Gastric Cancer”. Turkish Journal of Clinics and Laboratory, vol. 13, no. 2, 2022, pp. 188-94, doi:10.18663/tjcl.1039557.
Vancouver Birdal C, Dursun H, Kılınç OC. A Retrospective Analysis of Esophagus and Gastric Cancer. TJCL. 2022;13(2):188-94.


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