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Factors affecting need for hormone replacement after thyroid lobectomy

Yıl 2024, Cilt: 6 Sayı: 2, 181 - 184, 08.03.2024
https://doi.org/10.38053/acmj.1404137

Öz

Aims: The aim of this study is to determine the incidence and risk factors of postoperative hormone replacement in patients who underwent thyroid lobectomy.
Methods: Patients who underwent thyroid lobectomy in our clinic between January 2015 and January 2021 were retrospectively scanned. Age, gender, preoperative hemogram and thyroid function tests (TFT) were screened. During postoperative follow-up, current TFT, height, weight, thyroid hormone replacement status and hypothyroidism symptoms were questioned. Pathology reports were examined.
Results: The pathology (patological examination results of specimen of the patients) were nodular hyperplasia in 81.1% (n=30) and Papillary thyroid carcinoma (PTC) in 18.9% (n=7). While the need for hormone replacement developed in 37.8% (n=14) of the patients in the postoperative follow-up, it did not develop in 62.2% (n=23). It was determined that high preoperative thyroid stimulating hormone (TSH) significantly increased the need for postoperative hormone replacement (p<0.05). In addition, it was found that the need for hormone replacement increased significantly in patients whose pathology results were compatible with malignancy (p<0.05).
Conclusion: Malignancy and preoperative high TSH are important predictors of postoperative levothyroxine need.

Kaynakça

  • Nguyen XV, Job J, Fiorillo LE, Sipos J. Thyroid incidentalomas: practice considerations for radiologists in the age of incidental findings. Radiol Clin. 2020;58(6):1019-1031.
  • Cibas ES, Ali SZ. The 2017 bethesda system for reporting thyroid cytopathology. Thyroid. 2017;27(11):1341-1346.
  • Frates MC, Benson CB, Doubilet PM, et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab. 2006;91(9):3411-3417.
  • Verloop H, Louwerens M, Schoones JW, Kievit J, Smit JWA, Dekkers OM. Risk of hypothyroidism following hemithyroidectomy: systematic review and meta-analysis of prognostic studies. J Clin Endocrinol Metab. 2012;97(7):2243-2255.
  • Miller FR, Paulson D, Prihoda TJ, Otto RA. Risk factors for the development of hypothyroidism after hemithyroidectomy. Arch Otolaryngol Head Neck Surg. 2006;132(1):36-38.
  • Stoll SJ, Pitt SC, Liu J, Schaefer S, Sippel RS, Chen H. Thyroid hormone replacement after thyroid lobectomy. Surgery. 2009; 146(4):554-560.
  • Su SY, Grodski S, Serpell JW. Hypothyroidism following hemithyroidectomy: a retrospective review. Ann Surg. 2009;250(6): 991-994.
  • Curran RC, Eckert H, Wilson GM. The thyroid gland after treatment of hyperthyroidism by partial thyroidectomy or iodine 131. J Pathol Bacteriol. 1958;76(2):541-560.
  • Roy AD, Allan J, Harden RM. A follow-up of thyrotoxic patients treated by partial thyroidectomy. Lancet. 1967:290(7518):684-688.
  • Michie W, Pegg CA, Bewsher PD. Prediction of hypothyroidism after partial thyroidectomy for thyrotoxicosis. Br Med J. 1972;1(5791):13-17.
  • Gough AL, Neill RW. Partial thyroidectomy for thyrotoxicosis. Br J Surg. 1974;61(12):939-942.
  • Kennedy JS, Thomson JA. The changes in the thyroid gland after irradiation with 131I or partial thyroidectomy for thyrotoxicosis. J Pathol. 1974;112(2):65-81.
  • Tweedle D, Colling A, Schardt W, et al. Hypothyroidism following partial thyroidectomy for thyrotoxicosis and its relationship to thyroid remnant size. Br J Surg. 1977;64(6):445-448.
  • Andåker L, Johansson K, Smeds S, Lennquist S. Surgery for hyperthyroidism: hemithyroidectomy plus contralateral resection or bilateral resection? A prospective randomized study of postoperative complications and long-term results. World J Surg. 1992;16(4):765-769.
  • Griffiths NJ, Murley RS, Gulin R, Simpson RD, Woods TF, Burnett D. Thyroid function following partial thyroidectomy. Br J Surg. 1974;61(8):626-632.
  • Keogh JC, Grace PA, Brown HJ, Browne HJ. Hypothyroidism following partial thyroidectomy. Ir Med J. 1977;70(8):261-262.
  • Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL. Postoperative thyroid hormone supplementation rates following thyroid lobectomy. Am J Surg. 2020;220(5):1169-1173.
  • Vaiman M, Nagibin A, Hagag P, Kessler A, Gavriel H. Hypothyroidism following partial thyroidectomy. Otolaryngol Head Neck Surg. 2008;138(1):98-100.
  • Lee DY, Seok J, Jeong WJ, Ahn SH. Prediction of thyroid hormone supplementation after thyroid lobectomy. J Surg Res. 2015;193(1):273-278.
  • Moon HG, Jung EJ, Park ST, et al. Thyrotropin level and thyroid volume for prediction of hypothyroidism following hemithyroidectomy in an Asian patient cohort. World J Surg. 2008;32(11):2503-2508.
Yıl 2024, Cilt: 6 Sayı: 2, 181 - 184, 08.03.2024
https://doi.org/10.38053/acmj.1404137

Öz

Kaynakça

  • Nguyen XV, Job J, Fiorillo LE, Sipos J. Thyroid incidentalomas: practice considerations for radiologists in the age of incidental findings. Radiol Clin. 2020;58(6):1019-1031.
  • Cibas ES, Ali SZ. The 2017 bethesda system for reporting thyroid cytopathology. Thyroid. 2017;27(11):1341-1346.
  • Frates MC, Benson CB, Doubilet PM, et al. Prevalence and distribution of carcinoma in patients with solitary and multiple thyroid nodules on sonography. J Clin Endocrinol Metab. 2006;91(9):3411-3417.
  • Verloop H, Louwerens M, Schoones JW, Kievit J, Smit JWA, Dekkers OM. Risk of hypothyroidism following hemithyroidectomy: systematic review and meta-analysis of prognostic studies. J Clin Endocrinol Metab. 2012;97(7):2243-2255.
  • Miller FR, Paulson D, Prihoda TJ, Otto RA. Risk factors for the development of hypothyroidism after hemithyroidectomy. Arch Otolaryngol Head Neck Surg. 2006;132(1):36-38.
  • Stoll SJ, Pitt SC, Liu J, Schaefer S, Sippel RS, Chen H. Thyroid hormone replacement after thyroid lobectomy. Surgery. 2009; 146(4):554-560.
  • Su SY, Grodski S, Serpell JW. Hypothyroidism following hemithyroidectomy: a retrospective review. Ann Surg. 2009;250(6): 991-994.
  • Curran RC, Eckert H, Wilson GM. The thyroid gland after treatment of hyperthyroidism by partial thyroidectomy or iodine 131. J Pathol Bacteriol. 1958;76(2):541-560.
  • Roy AD, Allan J, Harden RM. A follow-up of thyrotoxic patients treated by partial thyroidectomy. Lancet. 1967:290(7518):684-688.
  • Michie W, Pegg CA, Bewsher PD. Prediction of hypothyroidism after partial thyroidectomy for thyrotoxicosis. Br Med J. 1972;1(5791):13-17.
  • Gough AL, Neill RW. Partial thyroidectomy for thyrotoxicosis. Br J Surg. 1974;61(12):939-942.
  • Kennedy JS, Thomson JA. The changes in the thyroid gland after irradiation with 131I or partial thyroidectomy for thyrotoxicosis. J Pathol. 1974;112(2):65-81.
  • Tweedle D, Colling A, Schardt W, et al. Hypothyroidism following partial thyroidectomy for thyrotoxicosis and its relationship to thyroid remnant size. Br J Surg. 1977;64(6):445-448.
  • Andåker L, Johansson K, Smeds S, Lennquist S. Surgery for hyperthyroidism: hemithyroidectomy plus contralateral resection or bilateral resection? A prospective randomized study of postoperative complications and long-term results. World J Surg. 1992;16(4):765-769.
  • Griffiths NJ, Murley RS, Gulin R, Simpson RD, Woods TF, Burnett D. Thyroid function following partial thyroidectomy. Br J Surg. 1974;61(8):626-632.
  • Keogh JC, Grace PA, Brown HJ, Browne HJ. Hypothyroidism following partial thyroidectomy. Ir Med J. 1977;70(8):261-262.
  • Wilson M, Patel A, Goldner W, Baker J, Sayed Z, Fingeret AL. Postoperative thyroid hormone supplementation rates following thyroid lobectomy. Am J Surg. 2020;220(5):1169-1173.
  • Vaiman M, Nagibin A, Hagag P, Kessler A, Gavriel H. Hypothyroidism following partial thyroidectomy. Otolaryngol Head Neck Surg. 2008;138(1):98-100.
  • Lee DY, Seok J, Jeong WJ, Ahn SH. Prediction of thyroid hormone supplementation after thyroid lobectomy. J Surg Res. 2015;193(1):273-278.
  • Moon HG, Jung EJ, Park ST, et al. Thyrotropin level and thyroid volume for prediction of hypothyroidism following hemithyroidectomy in an Asian patient cohort. World J Surg. 2008;32(11):2503-2508.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Genel Cerrahi
Bölüm Research Articles
Yazarlar

Adem Şentürk 0000-0002-7626-4649

Ahmet Tarık Harmantepe 0000-0003-2888-7646

Emre Gönüllü 0000-0001-6391-4414

Hakan Demir 0000-0001-5973-4605

Alp Ömer Cantürk 0000-0003-3641-7628

Emine Sena Cünük 0000-0001-9160-0121

Tuba Yavuz Akça 0000-0003-1730-5006

Yayımlanma Tarihi 8 Mart 2024
Gönderilme Tarihi 12 Aralık 2023
Kabul Tarihi 24 Şubat 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 6 Sayı: 2

Kaynak Göster

AMA Şentürk A, Harmantepe AT, Gönüllü E, Demir H, Cantürk AÖ, Cünük ES, Yavuz Akça T. Factors affecting need for hormone replacement after thyroid lobectomy. Anatolian Curr Med J / ACMJ / acmj. Mart 2024;6(2):181-184. doi:10.38053/acmj.1404137

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